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This article covers mechanism, clinical trial evidence, FDA-approved indications, boxed-warning safety, and the FTO, GLP1R, MC4R, and TCF7L2 variants that shape every GLP-1 response

This fact paved the way for the development of a GIP receptor agonist-based therapy for T2DM, looking also for the possibility of finding a combined GLP-1/GIP receptor agonist

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Palavicini SMS, Puton BMS, Jacques RA, Valduga E, Backes GT, Paroul N, Steffens C, Cansian RL
