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Independently of these peripheral actions, GLP-1RAs show direct cerebral effects in animal stroke models, such as reduction of infarct volume, apoptosis, oxidative stress, neuroinflammation, excitotoxicity, bloodbrain barrier permeability, and increased neurogenesis, neuroplasticity, angiogenesis, and brain perfusion
For Employers and PBMs: No Automatic Change, But Significant Leverage For employers, this announcement does not automatically lower GLP-1 costsPBM contracts remain as written
A reduction in insulin-stimulated glucose uptake was observed in PA-treated L6 cells, confirming IR
