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Description
Supporting a role of the NTS in mediating GLP-1's effects on food intake, adeno-associated virus (AAV) mediated knock-down of GLP-1R in the NTS results in higher food intake and meal size [699]

In a phase 2 dose-finding trial in adults with obesity or overweight, survodutide produced dose-dependent reductions in body weight and was described as a glucagon receptorGLP-1 receptor dual agonist

These medications work with hormone pathways involved in appetite regulation, fullness, digestion, and blood sugar control
Health 29 , 245254 (2006)

These symptoms generally appear during the first few weeks of treatment, particularly during dose escalation phases when the body is adjusting to the drug
