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How using GLP-1s have affected Gad psychologically The former "The Book of Mormon" star shared that he has wrestled philosophically with using GLP-1s for weight loss

2023 Aug 19;402(10402):613-626

It is important to note that, in the other large type 2 diabetes cardiovascular outcome trials, there were no statistically significant associations with the use of GLP-1/GIP agonists and negative eye outcomes

Other side effects include diarrhoea (up to 30% on semaglutide and 20% on tirzepatide), vomiting (25% vs 12% respectively), constant sinusistis/pharyngitis (up to 20%), headaches (15% vs 6%), abdominal pain (10% vs 5%)