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doi:10.1093/eurheartj/ehaa652 Nicholls SJ, Lincoff AM, Garcia M, et al

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In the recent STEP HFpEF DM trial, which studied the efficacy of semaglutide among patients with obesity-related HF with preserved ejection fraction (HFpEF) and T2D, a reduction in the time to first HF events was demonstrated in the intervention arm, but this was a secondary endpoint

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An alternative addiction transfer hypothesis asserts that following cessation of substance use, individuals may replace drug rewards with other substances (e.g., food) which stimulate similar neurobiological reward pathways

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