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161,168 The most significant pharmacokinetic alterations were reported following the administration of a single 5 mg dose of tirzepatide, with the C max and AUC values of ethinylestradiol decreasing by 59% and 21%, respectively, and those of norelgestromin by 55% and 22%, respectively (Table 4)

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Dopamine release in antidepressant-nave major depressive disorder: a multimodal [11C]-(+)-PHNO positron emission tomography and functional magnetic resonance imaging study

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