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Cardiologists, once peripheral to obesity management, now account for roughly one-third of new GLP-1 scripts, broadening the prescriber base

Additionally, some CNS effects may be mediated peripherally through vagal afferent activation or endocrine-to-neural relay mechanisms that secondarily influence brain function without requiring parenchymal drug accumulation [8]

Liraglutide mends cognitive impairment by averting Notch signaling pathway overexpression in a rat model of polycystic ovary syndrome

Rayner, C.K

These effects can help clients reduce caloric intake, working alongside lifestyle changes such as diet and exercise to promote significant weight loss