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GLP-1based therapies are associated with predictable GI adverse effects, most of which are mild to moderate and manageable

Latest review of the Tirzepatide dual receptor agonist GLP-1/GIP, summarizing five clinical trials in type 2-diabetic subjects.

GLP-1 RAs have been used for diabetes and found to improve CV outcomes in diabetic and nondiabetic patients

Over time, some patients may need to pause or stop therapy due to side effects, plateaus, or changing goals
