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Description
The semaglutide group had a 0.33 percentage point reduction in HbA1c ( P = .034), a 0.37 mmol/L decrease in total cholesterol ( P = .04) and a 0.29 mmol/L decline in LDL cholesterol ( P = .05) from baseline to 1 year
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Combining GIP and GLP-1R agonism was first discovered and reported a decade ago 40 and has now fully evolved as the GIP/GLP-1R co-agonist tirzepatide that can achieve more than 20% weight loss in obesity as well as offering superior benefits in diabetes
doi: 10.1002/dmrr.3207 97 ZhongTHeBLiXLeiKTangRZhaoBet al
