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Different GLP-1 receptor agonists have varying pharmacokinetic profiles and receptor binding characteristics

GLP-1 receptor agonists have been shown to increase dopamine and serotonin release in the brain, which may contribute to their effects on appetite and satiety

And the North Carolina State Health Plan Board of Trustees voted last year to end coverage of GLP-1s for state employees, after then-North Carolina Treasurer Dale Folwells office estimated in 2023 that the drugs were projected to cost the State Health Plan $1 billion over the next six years

Grover M, Bernard CE, Pasricha PJ, et al

Patient Perspective: Jennifer, a 41-year-old nurse, tried liraglutide first: "It definitely helped with appetite control, and I lost about 18 pounds over six months