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Metabolic improvements were assessed through non-diabetic markers: blood pressure, lipids, and inflammatory markers (see Cardiovascular Safety section above)

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It's crucial to consult with a trained aesthetic professional who can provide guidance on selecting the most appropriate treatment for you, considering your specific requirements and discussing the risks and benefits of each option

As an embodiment of the present invention, the base used in the coupling reaction in step (2) is an organic base or an inorganic base, and the organic base is any one of triethylamine, N-diisopropylethylamine, pyridine, piperidine, and aniline