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Consequently, there is increased production of cytokines derived from T cells, such as TNF-, IFN-, IL-2, IL-17, and granulocyte-macrophage colony-stimulating factor, in the synovial fluid, leading to joint inflammation[40]

doi: 10.1172/JCI186652, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 47

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