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If more Medicare beneficiaries with obesity or overweight gain access to GLP-1s based on other approved uses for these medications, that could reduce the cost of proposed legislation to lift the statutory prohibition on Medicare coverage of anti-obesity drugs

Moreover, the OXMQ3E peptide was unable to produce any weight loss in Glp1r -/- mice, suggesting that both GLP-1R and GCGR are required for weight loss to occur

Every medicine has risks and benefits

As a result, clinicians may begin therapy earlier, potentially improving outcomes and preventing complications

Zepbound and Mounjaro use the same active ingredient tirzepatide, similar to semaglutide, FDA-approved for people with obesity or overweight accompanied by diet and fitness