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Obesity was often overlooked at many pharmaceutical companies, and it took investing billions of dollars in the face of significant criticism to get us here

6.3 Neurodegenerative disorders Recent research indicates that GLP-1 receptor agonists are potentially advantageous for neurodegenerative disorders (Table 2), especially in light of the recognized association between diabetes and dementia

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Genetics also play a significant role in determining where stubborn fat persists

However, several investigations reported a lack of GLP-1R in tubules (Pyke et al., 2014