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Conversely, liver conditions like metabolic dysfunction-associated steatotic liver disease (MASLD), also known as non-alcoholic fatty liver disease (NAFLD) can increase the risk of HF due to systemic inflammation, oxidative stress, and metabolic disturbances [34, 35]

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Methods A systematic search using Medline and the Cochrane Library from inception to 29 September 2018 was performed to identify studies that semaglutide was used as a treatment for T2DM

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Differentiation amongst these agents is important, and there are several factors that will make assets from smaller companies attractive: 1) oral and infrequent dosing regimens, 2) ability to improve cardiometabolic outcomes along with weight loss, and 3) reduced GI side effects