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The authors theorise that microdosing Wegovy could help to limit gastrointestinal side effects, which are particularly common during dose escalations

Common early effects include mild nausea, reduced appetite, and occasional changes in digestion, which typically fade by week 34 as your body adapts

1 Weight loss results: Semaglutide 0.5 mg: -4.6 kg vs dulaglutide 0.75 mg: -2.3 kg Semaglutide 1.0 mg: -6.5 kg vs dulaglutide 1.5 mg: -3.0 kg Treatment difference: approximately double the weight loss with semaglutide at both dose levels Blood sugar control was also superior with semaglutide at all dose comparisons: Cardiovascular outcomes Both medications have demonstrated cardiovascular benefits, though in different trials

After we eat, GLP-1 (made in our intestines) helps signal fullness, slows the rate at which food leaves the stomach, and coordinates insulin and glucagon release to keep blood sugar levels in check
