pronounce tirzepatide in english How to (correctly!) Wacky Word Wednesday is back…

doi: 10.1056/NEJMra1806939

This is a realistic, common transition experience

Weight loss in women with PCOS can improve insulin sensitivity, lower androgens, and restore more regular ovulation

However, an unphysiologically large postprandial release of GLP1, for example, after gastric bypass surgery (Korner et al., 2007), might reach the circumventricular organs, and DPP4resistant GLP1 receptor agonists clearly have central actions, though whether this includes action on GLP1 receptors inside the BBB or is limited to direct activation of GLP1 receptors in the circumventricular organs outside the BBB, is less clear (Adams et al., 2018

Food and Drug Administration (FDA) has approved the Wegovy pill (once-daily oral semaglutide 25 mg) to reduce excess body weight and maintain weight reduction long term and to reduce the risk of major adverse cardiovascular events