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S5A), but not in Glp1r Ghsr neurons (Supplementary Fig

Bias between mini-G s and -arrestin-2 recruitment was determined similarly to earlier work (Pickford et al ., 2020), by subtracting the log /K values (Kenakin et al ., 2012) for each ligand in each pathway for each assay to determine log /K A (referred to here as LogR)

doi: 10.1093/jnen/60.8.759 [DOI] [PubMed] [Google Scholar] 160.Pastorino L, Sun A, Lu PJ, et al

Your body reads that as stress, even if its positive on the scale

When that valve weakens or opens more frequently, stomach acid irritates the esophageal lining, triggering the burning sensation you recognize as heartburn or GERD symptoms