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Description
As GLP-1 has been implicated as a mediator in the putative gutrenal axis (a rapid-acting feed-forward loop that regulates postprandial fluid and electrolyte homeostasis), direct actions on the kidney have been proposed

Infections: There is a potential risk for infections, particularly gastrointestinal infections
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A listing of GLP-1 focused clinical studies is available at ClinicalTrials.gov

M., Elmslie, J

Furthermore, our results can be generalised mostly to individuals with type 2 diabetes who are already on metformin-based background therapy, given that drug-naive individuals were recruited only in one study [22]