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Approval rates (CVS Caremark internal data, 2025): First submission approval: 34% Approval after one appeal: 58% Approval after second appeal or peer-to-peer review: 71% Final denial rate: 29% The most common denial reasons: Insufficient documentation of 90-day lifestyle intervention (41% of denials) BMI does not meet threshold or comorbidity not documented (28%) Step therapy not completed (19%) Prescriber not in-network or not qualified specialty (12%) The prior authorization process takes 3 to 14 business days for standard review

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The type and stage of the cancer, as well as a persons age and overall health, will affect which treatment doctors recommend

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