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Retatrutide has a half-life of approximately 6 days, meaning it takes 4 to 5 weeks to reach steady state at any given dose
It represents a new class of multi-receptor agonists for metabolic research

Direct answer: Long-term Semaglutide use may include persistent gastrointestinal symptoms, potential muscle loss, gallbladder issues, and rare risks like pancreatitis or thyroid concerns