why do glp 1 agonists cause nausea GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist Induced and Emesis in Preclinical Models — Hayes Lab Nausea & Vomiting from GLP-1
Description
GLP-1 drugs were a breakthrough, but not the final answer

10.1016/j.jacc.2021.12.011 31 HermansenK.BkdalT

Nausea, vomiting, dyspepsia, or abdominal distension in those taking GLP-1 agonists predict increased residual gastric contents

"Novo Nordisk launching the Wegovy pill on Ro from Day 1, and leveraging Ro's vertically integrated infrastructure, is an extremely innovative approach to increase access to the next generation of blockbuster drugs," said Zach Reitano, Ro co-founder and CEO

No Certainty Theres a lot of uncertainty with these estimates, which CBO admits
