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A structured approach can simplify this decision-making process: Assess cardiovascular and renal status : Patients with heart failure or kidney disease often benefit from SGLT2 inhibitors first
Patients who develop symptoms of pancreatitis (e.g., upper abdominal pain radiating to the back, nausea, vomiting) should be evaluated promptly, and tirzepatide should be discontinued if pancreatitis is confirmed
Samms, R
Just make sure to include all of these factors in your decision
Alarmingly, this has also applied to specialist clinic settings for those with T2DM and established CAD, including prior MI [162]
