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Carlat Verdict: To prevent metabolic side effects when beginning an antipsychotic, start with metformin, but consider a GLP-1 RA for patients who have already been on antipsychotics for a while with a BMI 30 kg/m 2 (or 27 kg/m 2 and obesity-related health problems)

The companys alleged knowledge of these adverse effects, combined with inadequate labeling updates, strengthens the legal basis for both compensatory and potentially punitive damages in individual cases

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33 A retrospective analysis of 164 patients with T2D who switched to OW semaglutide from either liraglutide or dulaglutide (REALiSeDM), having been on the initial GLP1RA for at least 3 months, also showed a reduction in HbA 1c following the switch

Low-income residents losing coverage will be advised to rely on diet and exercise, which experts say is unrealistic