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Description
Incretin-based therapies The year 2021 welcomed a game changer in the form of semaglutide for treatment of T2D in Singapore: Once-weekly subcutaneous (SC) semaglutide 1 mg (Ozempic®) and daily oral (PO) semaglutide (Rybelsus®)

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World Obesity Federation, World Obesity Atlas 2023 Unsurprisingly, weight loss medications have captured innovators attention as potential solutions, however, the obesity market has a history of many false dawns, as drugs in the past failed to deliver meaningful efficacy while some had serious safety issues, e.g., Fen-Phen, which was eventually withdrawn from the market due to cardiac risks3

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Orforglipron led to greater weight loss than semaglutide tablets and could offer more effective oral alternative to jabs
