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There was no significant difference in fasting plasma glucose (121.2 32.2 vs 116.6 25.0 mg/dl), HbA1c (5.9 0.6 vs 6.4 1.9%), HDL-cholesterol (37.1 10.3 vs 39.0 9.0 mg/dl), LDL-cholesterol (111.1 38.1 vs 91.3 33.0 mg/dl) between the obesity and non-obesity group (Table 1)

Secreted as PYY(136), it is then cleaved by the enzyme dipeptidyl peptidase 4 into PYY(336)

The FDA has recently approved generic versions of two other GLP-1 drugs, Victoza (liraglutide) and Byetta (exenatide)

Toast with turkey or crackers with tuna Simple, protein-aware, and small enough not to feel overwhelming

Older adults may benefit from GLP-1 therapy but require careful monitoring, while those with severe kidney disease need dose adjustments