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Do not double up to "catch up." Missing a dose during the microdose phase is less disruptive than during maintenance because the sub-therapeutic doses are not producing strong effects that would be lost

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OPM requires FEHB plans to cover at least one GLP-1 prescribed for weight loss, and this extends to any Part D or Medicare Advantage plan offered by an FEHB carrier

Additionally, risk factors include kidney issues, being aged 65 or older and excessive alcohol intake

Observations from the global registration Phase III trials suggest that tirzepatide (a novel dual GIP/GLP-1 receptor agonist) represent advancement over current GLP-1 analogues, providing enhanced glycaemic and weight benefits with similar gastrointestinal tolerability