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But once the drug is fully cleared, the underlying biology reasserts itself

Studies indicate that while GLP-1s can lead to substantial weight loss, bariatric surgery often results in greater total weight loss and better resolution of comorbidities, especially in patients with class II and III obesity [12] [13]

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However GLP-1s are not currently funded in the South African healthcare setting and so may not be available for that reason

survodutide is earlier in its Phase 3 program, with timelines that depend on its obesity and MASH trials reading out
