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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Vilar-Gomez E., Martinez-Perez Y., Calzadilla-Bertot L., Torres-Gonzalez A., Gra-Oramas B., Gonzalez-Fabian L., Friedman S.L., Diago M., Romero-Gomez M

Signs that microdosing may not be your best approach If you have been at a dose for four or more weeks with zero noticeable changes in appetite, energy, or food behavior, and you have experienced no GI side effects whatsoever, you may be someone whose receptor sensitivity requires higher doses to engage

The medicine is used together with a healthy diet and regular exercise

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