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The following evidence-based strategies can help patients maximise the benefits of treatment whilst minimising fatigue: Nutritional adequacy is paramount

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1,2 Yet, many of these drug molecules exhibit short systemic half-lives that necessitate frequent dosing to maintain therapeutic exposure, leading to poor patient adherence and significant peak-to-trough fluctuations that can drive adverse side effects

Vasomotor symptoms

This is one reason why GERD is more common in people with obesity
