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These medications, often referred to by their brand names Ozempic and Wegovy, contain semaglutide as an active ingredient and are used for weight loss and type 2 diabetes

Patients in whom heart failure (HF) or chronic kidney disease (CKD) is prevalent, should receive a treatment intensification with an SGLT-2 inhibitor with the respective evidence from clinical studies due to the respective data (7072)

Consider evaluating body composition using tools such as an InBody scale or DEXA scan to establish baseline values and monitor changes over time

Still, these findings are encouraging enough to warrant further research

The framework below summarizes evidence-based interventions with their documented mechanisms and expected timeframes for metabolic adaptation