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This underscores the need for integrated strategies combining pharmacotherapy with personalised dietary interventions and resistance exercise [24, 71], not only to preserve MM and support metabolic health but also to minimise the risk of nutritional deficiencies and sarcopenia [7981]

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PMID: 26458565

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Evidence: The SCALE clinical programme demonstrated significant benefits, with participants achieving an average weight loss of approximately 8 per cent of baseline body weight at 56 weeks, compared with around 3 per cent in those who received lifestyle intervention alone