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Pioneer 2: Efficacy of semaglutide and empagliflozin was studied on 703 subjects receiving once-daily oral 14.0 mg semaglutide (412), 25.0 mg empagliflozin (410)

Patients should keep their bodies hydrated and drink water regularly

To further explore the interaction between semaglutide and dopamine, semagltuide's suppressive effect on dopamine driven behaviours 24 , 25 was examined in alcohol-nave male and female rats

Potential side effects: While both medications are generally well-tolerated, its important to monitor for any side effects, particularly if they become severe or persistent

As the prevalence of MASLD continues to increase, these findings highlight the rapidly evolving treatment landscape and the potential for additional disease-specific therapies beyond resmetirom in the coming years