glp 1 does not work for me What if GLP-1s Don't Me? “GLP-1s just prove people don’t
Description
Effect of the dual glucosedependent insulinotropic peptide/gulcagonlike peptide 1 receptor agonist tirzepatide on lipid profile and waist circumference: a systematic review and metaanalysis
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doi: 10.1016/S22138587(22)001887 81 BradleyCLMcMillinSMHwangAYSherrillCH

GLP-1 receptor agonists and dual GLP-1/GIP co-agonists can produce substantial weight loss, but caloric restriction and weight loss trigger adaptive thermogenesis and neuroendocrine changes (reduced energy expenditure and increased appetite) that facilitate weight regain once therapy is discontinued

However, burping and bloating can occur with either formulation since both activate the same GLP-1 receptors
