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pmid:32047613 10

A 180-pound person needs at least 90 ounces (roughly 2.7 liters)

20 A 24-week randomized, double-blind, parallel-group trial enrolled 701 patients to assess the safety and efficacy of adding sitagliptin to ongoing metformin therapy

Spicy foods may increase digestive discomfort

Studies with a pragmatic design, high discontinuation rates, or shorter study durations could have limited overall exposure to the study GLP-1 RA, which ultimately could have dampened the ability to detect a difference if one existed
