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Unraveling the safety profile of glp-1 receptor agonists: Mechanistic insights with a focus on semaglutide

According to UK product information and clinical trials, nausea affects approximately 1540% of patients starting GLP-1 therapy, though the exact percentage depends on the specific medication, dose, and titration schedule used

This question concerns many patients prescribed glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda) for type 2 diabetes or weight management

It binds to its specific receptors on pancreatic beta cells, enhancing insulin secretion in response to postprandial hyperglycemia (Fig

The result is a split system