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Finan, B., Clemmensen, C., Zhu, Z., Stemmer, K., Gauthier, K., Mller, L.,

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Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors

Orforglipron is the first oral small molecule glucagon-like peptide-1 (GLP-1) receptor agonist, taken without food and water restrictions, to successfully complete a Phase 3 trial