tirzepatide heart failure trial SUMMIT: Improves Outcomes and Quality of Life For Patients With HFpEF and Obesity Tirzepatide Improves HFpEF Symptoms and
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Time in range (TIR) increased from 56.9% at baseline to 88.9%, 76.2% and 71.7% with CagriSema, semaglutide and cagrilintide, respectively [124]

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They provide longer-lasting effects but can take longer to kick in , making it important to dose them carefully

Of these, 92/129 subjects achieved a mW of 83.2 14.0 kg and mBMI of 30.6 4.4 kg/m 2 , with a mW and mBMI reduction respectively of 15.9 11.4 kg ( 15.0 8.7%) and 5.8 3.7 kg/m 2 (Fig
