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Side effects like nausea can increase dehydration risk, and suppressed appetite sometimes makes it easy to forget to drink enough

News Large-scale analysis of more than 400,000 Reddit posts has identified patient-reported symptoms associated with glucagon-like peptide-1 receptor agonists that may not be fully captured in clinical trials, with reproductive and temperature-related effects emerging as signals for further investigation in real world evidence A research team at the University of Pennsylvania, Philadelphia, USA, has used artificial intelligence to analyse more than 400,000 Reddit posts and identified patient-reported symptoms associated with glucagon-like peptide-1 (GLP-1) receptor agonists that may not have been explored in randomised clinical trials (RCTs) or regulatory documentation

Medications that act like GLP-1 receptor agonists, such as semaglutide, are designed to mimic the functions of GLP-1 in the body
Kiesewetter DO, Guo N, Guo J, Gao H, Zhu L, Ma Y, Niu G, Chen X

[DOI] [PubMed] [Google Scholar] 12.Glucagon-like peptide-1 (GLP-1) receptor agonists and their cardiovascular benefits-the role of the GLP-1 receptor
