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Liraglutide (an older GLP-1 medication) significantly increased the incidence of adverse events compared to both semaglutide and tirzepatide

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Semaglutide GLP-1 is now recommended by the FDA for chronic weight management in patients with a BMI greater than 30 kg/m2 or 27 kg/m2 but having at least one obesity-related comorbidity

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