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It is now available online as a research letter in Diabetes, Obesity & Metabolism.

A Korean study has found that probiotic strain Limosilactobacillus fermentum GB102 could enhance GLP-1 receptor agonist (RA) dulaglutide in obesity treatment. The study details that although GLP-1 RA treatments are effective for weight loss, when discontinued, weight regain is common

By including all English-language studies on muscle mass loss during GLP-1RA therapy in T2D and obesity from major scientific databases and clinical trial registries, this narrative review synthesizes the current knowledge on the epidemiology and mechanisms of muscle loss in diabetes and obesity, with a focus on the impact of GLP-1RAs therapy

Here we investigated the effects of the GLP-1 agonist exenatide on palatability-driven feeding regulation in adult male rhesus macaques (n=5) using a novel operant food intake paradigm with four meal schedule conditions where two types of pellets with different palatability values were offered as meal in all combinations in two consecutive daily feeding sessions (S1 and S2)

Our researchers found people with a "responsive" neurobeachin (NBEA) gene score were up to 120% more likely to lose more than 10% of their weight with semaglutide