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Dehydration can cause muscle cramps, and Wegovy's gastrointestinal side effects, such as nausea, vomiting, or diarrhea, may increase the risk of dehydration

In young adults, the number of those dispensed liraglutide, dulaglutide or exenatide was greatest in 2020 and 2021, whereas the number dispensed injectable semaglutide for type 2 diabetes was greatest in 2022 and 2023

Some researchers suggest that GLP-1 drugs may even reduce the activity of cells that produce collagen and elastin, which could further limit the skins ability to rebound
Patients experiencing significant gastrointestinal side effects from semaglutideparticularly nausea, vomiting, or diarrheashould avoid alcohol until these symptoms resolve
e , Pharmacokinetics of peptide 2 (1 mg kg 1 ), peptide 5 (1 mg kg 1 ) and peptide 8 (0.5 mg kg 1 ) following intravenous administration in male Sprague Dawley rats