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Description
Time-of-onset analysis revealed no consistent mechanism for the latency of SSIBs in patients receiving GLP-1RAs
Interestingly, glucagon-like peptide-1 receptor agonists (GLP-1RAs), used in the treatment of T2DM and obesity, are known to show pro-cognitive and neuroprotective properties, and exert modulatory effects on immune, endocrine and metabolic processes in the central nervous system
CagriSema and Amycretin work on the GLP-1 and amylin receptors, Retrarutide on GLP-1, GIP and glucagon, Survodutide, Mazdutide, Pemvidutide and Efinopegdutide on GLP-1 and glucagon and still more are coming
However, the current literature reveals a lack of in vivo studies on specific GLP-1R agonists such as semaglutide, necessitating further research to elucidate its precise mechanisms and effects, particularly in cancer
as the diagnosis of clinical obesity will be redefined, while evidence substantiating the value of AOMs begins to accumulate in the real world
