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On the other hand, a recent meta-analysis examined the adverse CV events of tirzepatide, including seven RCTs [109]

Patients should be aware that gastrointestinal symptoms often improve with time, and that treatment benefits should be weighed against side effects during follow-up appointments
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Patients are encouraged to track changes in body weight, measurements, appetite, and energy, as well as non-scale changes such as better sleep or improved mood, and the care team uses this information to refine the plan so it remains both safe and effective over time

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