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Their primary mechanisms of action include: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood sugar levels with a low risk of hypoglycaemia when used alone (though risk increases when combined with insulin or sulfonylureas) Suppressing glucagon release from pancreatic alpha cells, reducing hepatic glucose production Slowing gastric emptying , which prolongs the feeling of fullness after meals Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger and food intake These combined effects result in improved glycaemic control for people with diabetes and significant weight loss

It helps explain why the right treatment plan is not just about the medication itself

It is particularly beneficial for patients who need to manage their blood sugar levels but may not be candidates for medications that rely on insulin secretion or action due to various reasons, such as a risk of hypoglycemia or insufficient pancreatic insulin production

Hashimoto's is not just a thyroid problem

Xiao Q, Boushey RP, Cino M, et al