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If you have Type 2 diabetes with obesity, cardiovascular disease, kidney disease, or simply inadequate control on current medications, GLP-1 treatment deserves serious consideration

"Constipation from GLP-1s can be compounded by the fact that people are eating less," says Hamilton, "resulting often in less fiber consumption and less stool bulk overall." Many people also drink less fluid to avoid feeling overly full on GLP-1 medications, which can also lead to constipation

N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I

Zhang Q, Delessa CT, Augustin R et al (2021) The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

[DOI] [PubMed] [Google Scholar] Nuako A, Tu L