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Adults meeting the studys obesity criteria, who newly initiated tirzepatide or semaglutide, were identified and compared with matched individuals who started naltrexone-bupropion, phentermine, or phentermine-topiramate

The list price is $1,349 per package, which most people do not pay directly

What This Means for You If youre considering GLP-1 medications, talk with your healthcare provider about the potential benefits and risks

These medications work by mimicking the effects of natural hormones in the body, leading to reduced appetite and improved metabolic function

3A, B, both semaglutide and calorie restriction elevated the expression of METTL3/14, PDX1, AKT-1, INSR, IRS-2, and IGF1R in obese mice