can semaglutide cause skin pain Sensitivity? What to Know Ozempic® Face: What is it
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doi: 10.1016/j.ceca.2012.03.003

The SURMOUNT-5 trial (published in NEJM, 2025) demonstrated mean weight loss of 20.2% with tirzepatide versus 13.7% with semaglutide over 72 weeks in adults with obesity but without diabetes [10]
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The authors concluded it appears effective and generally safe
What matters most is that medication-based weight loss should be handled responsibly
