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Description
A new ligand against the GPCR GLP-1R acts as a positive allosteric modulator, binding both the receptor and the orthosteric ligand, accessing the peptide ligand within the interface between transmembrane domains 1 and 2 of the receptor.

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Read a testimonial highlighting a patients life-changing transformation on semaglutide and see his inspiring before and afters.

Research shows semaglutide improved the walking abilities and quality of life of patients with peripheral artery disease and type 2 diabetes.
