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Weight Loss Programs GLP-1 Analogs / Incretin mimetics: Ozempic, Wegovy, Semaglutide, Mounjaro and Tirzepatide For patients with type 2 diabetes, insulin resistance or obesity, these medications dosed as a 1x a week injection help patients lose weight and manage their glucose levels by slowing gastric emptying, reducing appetite and improving insulin sensitivity

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Metformin Metformin is the first-line drug in the treatment of diabetes and can reduce gluconeogenesis and liponeogenesis, lower systemic inflammation, increase GLP1 levels, and modify intestinal microbiota, all of which have potential beneficial effects on the liver [81]

Less sleep means you have more ghrelin and less leptin, so youll feel hungrier, crave high-calorie foods, and eat more than you need

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